ܠܦܦܐ:Cyclotide biosynthesis.png
ܥܓܪܐ ܕܓܠܚܐ: 800 × 545 ܦܩܣܠ. Other resolutions: 320 × 218 ܦܩܣܠ | 640 × 436 ܦܩܣܠ | 1,021 × 695 ܦܩܣܠ.
ܠܦܦܐ ܫܪܫܝܐ (1,021 × 695 ܦܩܣܠ، ܥܓܪܐ ܕܠܦܦܐ: 132 KB، ܐܕܫܐ ܕ MIME: image/png)
ܦܣܝܩܬ̈ܐ
| Description |
English: The cyclotide precursor is comprised a hydrophobic signal peptide that targets the precursor to the Endoplasmic Reticulum (ER), an N-terminal propeptide that then targets it to the vacuole, a cyclotide domain and a final C-terminal propeptide necessary for cyclisation.
The cyclotide domain folds in the ER, after which it is trafficked to the vacuole and the cyclotide domain is cyclised by an asperginyl endopeptidase. (PDB: 1WN8, 1NB1) |
| ܣܝܩܘܡܐ | |
| ܡܒܘܥܐ | Own work |
| ܣܝܘܡܐ | Evolution and evolvability |
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| ܗܫܝܐ | 05:24, 13 ܒܚܙܝܪܢ 2016 | | 1,021 × 695 (132 KB) | Evolution and evolvability | opaque background |
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